Herpes can be shocking, confusing, and can get one very scared. A single positive test comes with no indication or symptoms and a desperate need for clarification. And a need to understand completely different tests, examinations, and nuances gets introduced. At the same time, what needs to be remembered is any sort of medical test is bound to contain flaws in one shape or another.
In this blog, I will take you through the various levels of accuracy stemmed from multiple examinations set in place to check for herpes, the variances of positive result checks, and most importantly the root causes of inaccurate aforementioned results. All of which is aimed to aid every one of you with optimal decision making layers concerning sexual health. Heads up to every one of you who wish to gain much-required confidence while handling the aspects of sexual health.
Reasoning and contributing aspects behind an inaccurate positive result
The first steps often look like they deal with precise results as receiving and identifying certain relevant antibodies, geonomes, and other markers promising to deliver accurate output. Despite this being straightforward, there are either too many or too few components, stalling these tests outside the realms of perfection these tests indulge inside. Gaps stem from many external factors blurring the boundary of accuracy, some of them are as follows:
1.Other Markers Overlapping With Existing Lesions
One of the main reasons for a false positive is antibody cross-reactivity. Herpes antibody tests, such as IgG and IgM, detect your body’s immune response to the herpes virus (HSV-1 or HSV-2). However, your immune system produces similar antibodies for other infections, including:
- Epstein-Barr virus (linked to mononucleosis).
- Cytomegalovirus (CMV).
- Varicella zoster virus (causes chickenpox and shingles).
Sometimes, the test cannot differentiate these antibodies from herpes antibodies, leading to a positive result even though you aren’t infected with herpes.
2. Lab Errors and Testing Inaccuracies
No laboratory examination is mistake-proof. Contamination of samples, poor sample management, and equipment failures during test analysis can all alter results. Other factors include variation between techniques or poorly calibrated machines.
Errors also cook at human hands. Mislabeling samples or assigning incorrect results can lead to incorrect diagnosis.
3. Specific Medical Conditions
Some body illness may interfere with accuracy. For instance:
- Chronic autoimmune disease can, at times, cause peculiarity in antibody response, which confuses the tester.
- Pregnancy appears to change the body’s system governing its defenses, at times resulting in incorrect affirmative answer in diagnosis tests measuring antibodies.
These situations may not be frequent but emphasize how having a medical history is essential when interpreting the results of any of the tests.
Different Methods of Herpes Testing and their Accuracy
Testing for herpes involves different methods, and each has its strengths and weaknesses. Understanding these can provide clarity when interpreting your results.
1. Antibody Tests (IgG and IgM)
- IgG Test
The IgG test measures antibodies that develop weeks after exposure. It’s highly reliable for detecting past infections but is not useful for identifying recent ones. False positives can occur due to cross-reactive antibodies (as mentioned earlier).
- IgM Test
The IgM test detects antibodies produced early after infection. However, its accuracy is questionable. IgM tests have a high rate of false positives and are not specific for herpes; many experts recommend avoiding IgM tests altogether for diagnosing herpes.
2. Viral Culture
How to diagnose someone with herpes actually involves taking a sample from an active sore and testing to see if the live herpes virus can be cultured. Cultures are very specific, but may also fail to get the infection if the sample lacks sufficient virus. It can only be done when sores are present, so it is ruled out as an option in asymptomatic cases.
3. PCR (Polymerase Chain Reaction) Tests
Considered the “golden test” for herpes diagnosis, PCR tests are said to contain the virus’s DNA in them in very fine quantities. Their accuracy is exceptionally high, even if the amounts are scarce. Still, they remain susceptible to lab blunders or contamination.
Comprehending the testing method that was used is important when evaluating the reliability of your herpes diagnosis. If you are unclear about the kind of test you had, consult your healthcare provider for further information.
What to do If you receive a Positive result
The words “positive test result” can be terrifying, particularly for something as socially stigmatized as herpes. Here’s how to remain level-headed and rational about the situation:
1.Obtain a Confirmatory Test
One singular result from a test tells you nothing. Go and request a confirmatory test, preferably one with a less subjective method, like a PCR test. The confirmatory test aids in discounting false positives which paint a better picture of your health.
2.Seek Guidance from a Healthcare Professional
Using social media and other online sources is not advisable. Seek out a professional who you can rely on. A healthcare provider will be able to:
- Explain your test type and results.
- Recommend additional testing, if needed.
- Help you understand your risk factors and create a plan tailored to your situation.
This step is also crucial for emotional support, as a professional can help you manage the stress and stigma associated with the diagnosis.
3.Think About Retesting After a Specific Duration
Retaking the test too early may lead to vague and meaningless results. Striking a balance when retaking the test is paramount, as the provider needs to determine the right timeline to follow the initial testing for results. Follow-ups after some time are most suitable for confirming your status.
4.Understand the Condition and Its Treatment
Fear is most often derived from lack of knowledge. The opportunity to learn about herpes, its signs, and treatments should be embraced fully. It gives you the independence to address your information gaps and help you take decisions relative to your well-being.
Why Accurate Testing Matters
Having the right set of information regarding sexual health is fundamental even when tests are being taken. Positivity of results adds unnecessary pressure on mental health, damage relationships, and impair personal life. Consulting with the right healthcare provider and focusing on getting the right set of tests aids in taking the correct steps without worrying needlessly.
Final Thoughts on Diagnosing Herpes
esting for herpes adds valuable information to helping assess one’s sexual health. With that said, there are negative implications to the tests as well. Positives that are wrong do, while not so common, happen from cross-testing, testing facilities, or other health-related issues. Within any process, understanding outcomes helps remove the blindfolds.
Questioning provided results should encourage the individual to seek out second opinions. Being educated on the condition opens the doors to a variety of testing approaches that can be decided with healthcare specialists.
When herpes is diagnosed accurately, it enables you to make reasoned decisions concerning your health and relationships. Here, information is valuable, and so is in this instance.
Herpes experts H. Hunter Handsfield, MD, and Kees Reitmeijer, MD, PhD, explain the types of herpes tests available, what tests are preferred for those with or without symptoms, and what test to avoid. See more of their conversation on sexualhealthTV.org.